In 2008, when the Cancer Prevention and Research Institute of Texas embarked on its mission to cure cancer, the $3 billion program was welcomed with fanfare by voters who had passed a constitutional amendment to establish it.

Four years later, CPRIT’s future is far from certain, as the quasi-governmental agency and its fast-shrinking cast of advisers face accusations of impropriety and criminal and civil investigations.

The Texas attorney general, Travis County district attorney and state auditor’s office are all embroiled in investigations into whether CPRIT officials broke the law in their distribution of grant funds to cancer research ...

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